SUBSTITUTED PIPERIDINES AS NOVEL MDM2-P53 INHIBITORS

摘要

The present invention provides compounds having formula (II) or formula (III ) and the pharmaceutically acceptable salts thereof; wherein X, n, and R1-R12 are defined herein. The invention also provides a pharmaceutical composition comprising a therapeutically effective amount of a compound represented by formula (II) or (III) and a pharmaceutically acceptable carrier or excipient . The compounds are useful for treating cancer.