发明名称 PROCESS FOR PREPARATION OF DRONEDARONE BY OXIDATION OF A HYDROXYL GROUP
摘要 The invention relates to a novel process for the preparation of dronedarone (I) and pharmaceutically acceptable salts thereof;which comprises oxidizing a compound of formula (VI), or a salt thereof;and the obtained product is isolated and, if desired, converted into a pharmaceutically acceptable salt thereof.;Further aspects of the invention include the novel intermediary compound of formula (VI) and process for the preparation thereof.
申请公布号 US2016272606(A1) 申请公布日期 2016.09.22
申请号 US201615170646 申请日期 2016.06.01
申请人 SANOFI 发明人 HUSZÁR Csaba;HEGEDUS Adrienn;DOMBRÁDY Zsolt
分类号 C07D307/80 主分类号 C07D307/80
代理机构 代理人
主权项
地址 Paris FR