发明名称 |
PEPTIDES HAVING INHIBITING ACTIVITY ON THE PRODUCTION OF NITRIC OXIDE |
摘要 |
The present invention relates to a compound of the formula (I)wherein R1 is benzofuranyl substituted by halogen, or styryl substituted by halogen; R2 is substituted hydroxy, substituted mercapto or substituted sulfonyl; and X is or pharmaceutically acceptable salts thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof possess a strong inhibitory activity on the production of nitric oxide (NO), and are useful f or prevention and/or treatment of NO-mediated diseases in human being and anima ls.
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申请公布号 |
CA2433582(A1) |
申请公布日期 |
2002.07.18 |
申请号 |
CA20012433582 |
申请日期 |
2001.12.18 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
SHIMA, ICHIRO;SATO, KENTARO;ISHIBASHI, NAOKI;OHKAWA, TAKEHIKO;IMAMURA, KENICHIRO |
分类号 |
A61K38/00;A61K31/436;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/14;A61P11/00;A61P11/06;A61P13/12;A61P15/00;A61P15/10;A61P17/00;A61P17/04;A61P19/02;A61P19/06;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/16;A61P25/28;A61P27/02;A61P27/06;A61P27/10;A61P27/12;A61P27/14;A61P29/00;A61P31/04;A61P31/12;A61P31/22;A61P35/00;A61P35/04;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K5/06;C07K5/078;(IPC1-7):C07K5/078;A61K38/05 |
主分类号 |
A61K38/00 |
代理机构 |
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