VERFAHREN UND VORRICHTUNG ZUM ABGEBEN VON MEDIKAMENTEN IN AEROSOLFORM

摘要

An apparatus for producing aerosolized doses of a medicament which comprises a reservoir containing a powdered medicament to be aerosolized, the powdered medicament comprising a protein or polypeptide. The apparatus further comprises a means for aerosolizing the medicament in a chamber, the chamber comprising a mouthpiece. The apparatus also includes a means for transferring substantially the entire volume of the aerosolized medicament from the aerosolizing means from the chamber. In one form of the apparatus, 40% by weight of the powder medicament will remain aerosolized and suspended within the chamber following the transfer of the aerosolized medicament. In another form of the apparatus the volume of the aerosolized medicament is between 9.24% and 21.9% of the volume of the chamber once the medicament has been transferred.