发明名称 |
COMBINATION OF SELECTIVE FACTOR VIIA AND/OR XIA AND PLASMA KALLIKREIN INHIBITORS |
摘要 |
The present invention relates to a novel pharmaceutical combination for treating thromboembolic and/or inflammatory diseases, wherein the combination has: (a) a first therapeutic agent independently selected from the group consisting of a selective Factor VIIa inhibitor, a selective Factor XIa inhibitor, a combination of the selective Factor VIIa and XIa inhibitors, or pharmaceutically acceptable salt forms thereof; and (b) a second therapeutic agent comprising a selective plasma kallikrein inhibitor or a pharmaceutically acceptable salt form thereof. The instant invention is also directed to a method and composition suitable for treating thromboembolic and/or inflammatory diseases using the novel combinations. |
申请公布号 |
WO2006089005(A3) |
申请公布日期 |
2006.12.21 |
申请号 |
WO2006US05439 |
申请日期 |
2006.02.15 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY;SEIFFERT, DIETMAR, A.;KNABB, ROBERT, M. |
发明人 |
SEIFFERT, DIETMAR, A.;KNABB, ROBERT, M. |
分类号 |
A61K45/06;A61K38/17;A61P7/02;A61P29/00 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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