FAST FLUORESCENCE IMAGING DEVICE FOR DIFFUSE OPTICAL TOMOGRAPHY

摘要

The invention relates to a device for imaging an interior of a turbid medium (25) comprising: a) a receiving volume (20) for accommodating the turbid medium (25); b) a light source (5) for emitting excitation light, with the excitation light chosen such that it causes fluorescent emission in a fluorescent agent in the turbid medium (25); c) coupling means for optically coupling the light source (5) to the receiving volume (20), with the coupling means comprising an entrance position for light from which to irradiate the receiving volume (20); d) a photodetector unit (15) for detecting fluorescence light emanating from the receiving volume (20) as a result of the irradiation of the turbid medium (25) with excitation light from the light source (5). According to the invention the device is arranged to couple excitation light from the light source (5) into the receiving volume (20) from multiple entrance positions for light relative to the turbid medium (25) simultaneously. Multiple entrance positions for light may be created by coupling excitation light into the receiving volume (20) from M discrete entrance positions for light chosen from a plurality of N discrete entrance positions for light (M=N) or by coupling excitation light into the receiving volume (20) from multiple entrance positions for light with at least a subset of the multiple entrance positions for light forming a continuum. An example of the latter option is the use of a spatially extended flash lamp.