MODULATORS OF SYNDECAN-2 AND USES THEREOF

摘要

Modulators of syndecan-2, such as an antibody to syndecan-2 that cross-links syndecan-2 on the cell surface or a syndiecan-2 polypeptide that interferes with syndecan-2 receptor binding, is used to regulate a Th17 mediated disease such as an autoimmune disease, fibrosis or cancer.

主权项

1. A method of treating at least one disorder selected from the list consisting of an autoimmune disorder, fibrosis and a cancer, comprising the steps of
identifying a subject in need of treatment for at least one disorder selected from the list consisting of an autoimmune disorder, a fibrotic disorder and a cancer; and administering a dosage regimen of a Th17 inhibitor to the subject.