发明名称 New voltage-dependent potassium channel and its use to develop therapeutic medicine
摘要 <p>Potassium channel protein (I) Kv6.2 is new. (I) has a sequence of 467 (human) or 482 (murine) amino acids (given in the specification) or is a homolog, derivative or fragment of these with the same electrobiological, pharmacological and/or biological activity, and/or immunogenicity. Independent claims are also included for the following: (1) potassium channel (A) containing at least one (I); (2) nucleic acid (II) encoding (I); (3) vector containing at least one copy of (II); (4) host cells transformed with this vector; (5) recombinant production of potassium channels by culturing eukaryotic cells of (4); (6) identifying and testing substances (A) that can open, close, or (in)activate potassium channels, or alter their biophysical properties; and (7) antibodies (Ab) that bind to (I).</p>
申请公布号 EP1944370(A1) 申请公布日期 2008.07.16
申请号 EP20080004552 申请日期 1999.08.06
申请人 EVOTEC AG 发明人 NETZER, RAINER;PONGS, OLAF
分类号 C12N15/12;A61K38/00;C07K14/705;C07K16/28;C12Q1/68;G01N33/50;G01N33/68 主分类号 C12N15/12
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