摘要 |
PROBLEM TO BE SOLVED: To provide a method of selectively removing solutes, metabolites, and proteins from blood or plasma. SOLUTION: The method comprises: placing blood or plasma from the subject in a first solvent stream, the first solvent stream being separated from a second solvent stream by an electrophoretic membrane; applying an electric potential between the two solvent streams causing movement of metabolic contaminants from the blood or plasma through the membrane into the second solvent stream while cellular and biomolecular components of the blood or plasma are substantially retained in the first sample stream, or if entering the membrane, being substantially prevented from entering the second solvent stream; optionally, periodically stopping and reversing the electric potential to cause movement of any cellular and biomolecular components of the blood or plasma having entered the membrane to move back into the first solvent stream. By the treatment described above, after removing a desired amount of metabolic contaminants from the blood or plasma in the first solvent stream, the treated blood or plasma in the first solvent stream is returned to the subject. COPYRIGHT: (C)2009,JPO&INPIT
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