发明名称 NOVEL TETRAHYDROPYRIDOPYRIMIDINES AND TETRAHYDROPYRIDOPYRIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
摘要 The invention provides novel compounds having the general formula (I): wherein R1, R2, R3, Q, U,W, Z, X and Y are as described herein, compositions including the compounds and methods of using the compounds. These compounds are HbsAg inhibitors and are useful as medicaments for the treatment or prophylaxis of HBV infection.
申请公布号 WO2016107832(A1) 申请公布日期 2016.07.07
申请号 WO2015EP81257 申请日期 2015.12.28
申请人 F. HOFFMANN-LA ROCHE AG;HOFFMANN-LA ROCHE INC. 发明人 CHENG, ZHANLING;WANG, MIN;YANG, SONG
分类号 A61K31/444;A61K31/506;A61K31/519;A61P31/20;C07D471/04 主分类号 A61K31/444
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