SURFACE ACOUSTIC WAVE SENSOR FOR INFLUENZA DETECTION

摘要

An influenza detector for detecting a targeted influenza virus and a surface acoustic wave (SAW) sensor for Influenza A virus detection in liquid are provided. The influenza detector includes a liquid environment, the surface acoustic wave (SAW) sensor and an influenza specific binding agent such as an antibody. The agent is immobilized on a surface of the SAW sensor for selectively capturing an analyte for the targeted influenza virus. The SAW sensor is in contact with the liquid environment and includes a substrate comprising a piezo-electric material for producing a surface acoustic wave signal in response to an applied electric field and an insulative layer formed on top of the substrate and having a functionalized surface formed thereon for selectively immobilizing the influenza specific binding agent, the functionalized surface being in contact with the liquid environment. The surface acoustic wave signal produced by the SAW sensor changes in response to the analyte for the targeted influenza virus being present in the liquid environment and being captured by the influenza specific binding agent immobilized on the functionalized surface of the insulative layer of the SAW sensor.

主权项

1. An influenza detector for detecting a targeted influenza virus, the influenza detector comprising:
a liquid environment; a surface acoustic wave (SAW) sensor in contact with the liquid environment; and a targeted bioactive influenza species immobilized on a surface of the SAW sensor for selectively capturing an analyte for the targeted influenza virus, wherein the SAW sensor comprises:
a substrate comprising a piezoelectric material for producing a surface acoustic wave signal in response to an applied electric field; andan insulative layer formed on top of the substrate and having a functionalized surface formed thereon for selectively immobilizing the targeted bioactive influenza species, the functionalized surface being in contact with the liquid environment, andwherein the surface acoustic wave signal produced by the SAW sensor changes in response to the analyte for the targeted influenza virus being present in the liquid environment and being captured by the targeted bioactive influenza species immobilized on the functionalized surface of the insulative layer of the SAW sensor.