发明名称 |
SURFACES COMPRISING ATTACHED QUORUM SENSING MODULATORS |
摘要 |
The invention relates to compositions comprising QS modulating molecules attached to a surface via a linker. This QS modulator attached surface can then be used to modulate QS, biofilm production, biofilm streamer production and/or virulence factor production. These QS modulator attached surfaces can be used to treat areas known to contain human pathogens notorious for causing hospital-acquired infections as well as fatal infections that occur outside of health care settings. Other surfaces that can be coated according to embodiments of the invention include abiotic materials, such as intravenous catheters, implants, medical devices, and cooling towers. Preferred microorganisms that can be treated with the compositions of the invention include, but are not limited to S. aureus and/or P. aeruginosa. |
申请公布号 |
WO2016176146(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
WO2016US29213 |
申请日期 |
2016.04.25 |
申请人 |
THE TRUSTEES OF PRINCETON UNIVERSITY |
发明人 |
BASSLER, Bonnie L.;STONE, Howard A.;KIM, Min Young;MUIR, Thomas William;ZHAO, Aishan |
分类号 |
A01N25/08;A01N25/10;A01N43/647;A01P1/00 |
主分类号 |
A01N25/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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