发明名称 |
AZA SPIRO ALKANE DERIVATIVES AS INHIBITORS OF METALLPROTEASES |
摘要 |
The present invention provides a compound of Formula (I) or Formula (II): enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula (I) and (II) are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions. |
申请公布号 |
HK1086494(A1) |
申请公布日期 |
2017.01.06 |
申请号 |
HK20060106647 |
申请日期 |
2006.06.09 |
申请人 |
Incyte Holdings Corporation |
发明人 |
YAO, Wenqing;ZHOU, Jincong;XU, Meizhong;ZHANG, Fenglei;METCALF, Brian |
分类号 |
C07D;A61K;A61K31/4188;A61K31/424;A61K31/428;A61K31/4747;C07D471/10;C07D491/10;C07D497/10 |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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