Medical Devices for Local Bioactive Delivery

摘要

Medical devices for local bioactive delivery are described. A medical device includes a first biodegradable layer, a second biodegradable layer, and a bioactive disposed between the first and second biodegradable layers. The first and second biodegradable layers are positioned such that a surface of the first biodegradable layer faces a surface of the second biodegradable layer and such that a peripheral portion of one biodegradable layer is folded over a peripheral portion of the other biodegradable layer. Methods of making medical devices and methods of using medical devices are also described.

主权项

1. A medical device for delivering a bioactive, said medical device comprising:
a first biodegradable layer having a first peripheral edge, first and second opposing surfaces, and a first peripheral portion including portions of the first and second opposing surfaces and a portion of the first peripheral edge, the first layer having a first area; a second biodegradable layer having a second peripheral edge, third and fourth opposing surfaces, and a second peripheral portion including portions of the third and fourth opposing surfaces and a portion of the second peripheral edge, the second layer having a second area that is less than the first area; the first and second biodegradable layers positioned such that the second surface faces the third surface; the first peripheral portion folded over the second peripheral portion to form a triple laminate structure in which a portion of the second surface contacts a portion of the fourth surface; and a bioactive disposed between the first and second biodegradable layers.