发明名称 Pyrazoloquinoline derivative
摘要 A compound represented by formula (I) or a pharmacologically acceptable salt thereof which has an inhibitory effect on PDE9 and, therefore, is expected as being capable of increasing the cGMP level in the brain. Since the inhibitory effect on PDE9 and an increase in the cGMP level contribute to improvement in learning and memory behavior, the aforesaid compound or a pharmacologically acceptable salt thereof would be available as a remedy for cognitive dysfunction in Alzheimer's disease. In formula (I): R
申请公布号 AU2012319549(B2) 申请公布日期 2016.07.28
申请号 AU20120319549 申请日期 2012.10.04
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 NORIMINE, YOSHIHIKO;TAKEDA, KUNITOSHI;HAGIWARA, KOJI;SUZUKI, YUICHI;ISHIHARA, YUKI;SATO, NOBUAKI
分类号 C07D471/04;A61K31/437;A61K31/444;A61K31/506;A61P25/28;A61P43/00 主分类号 C07D471/04
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