Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions

摘要

Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.

主权项

1. A system for producing an asynchronous neural response in a patient, the system comprising:
a pulse generator having a machine-readable medium with first instructions that, when executed, cause the pulse generator to transmit an electrical stimulation signal having a frequency, and second instructions that, when executed adjust the frequency of the electrical stimulation signal; an electrode coupleable to the pulse generator to deliver the electrical stimulation signal to a target neural population of the patient; and a sensor positionable to detect a neural response to the electrical stimulation signal, wherein the second instructions adjust the frequency of the electrical stimulation signal in response to an input from the sensor.