发明名称 |
INDAZOLYL THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE |
摘要 |
The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting Rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an N-(5-[5-[(1H4ndazol-5-yl)amino]-1,3,4-thiadiazol-2-yl]pyridin-3-yl)acetamide compound. |
申请公布号 |
WO2016138335(A1) |
申请公布日期 |
2016.09.01 |
申请号 |
WO2016US19678 |
申请日期 |
2016.02.26 |
申请人 |
LYCERA CORPORATION |
发明人 |
AICHER, Thomas, Daniel;PADILLA, Fernando;TOOGOOD, Peter, L.;CHEN, Shoujun |
分类号 |
C07D417/12;A61K31/433;A61K31/437;A61K31/4375;A61K31/4412;A61K31/4439;A61K31/454;A61K31/496;A61K31/497;A61K31/4985;A61K31/506;A61K31/513;A61K31/5355;A61K31/5377;C07D417/14;C07D471/04;C07D471/12;C07D471/22;C07D498/04;C07D513/04 |
主分类号 |
C07D417/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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