发明名称 POLOXAMER-BASED INTRALESIONAL INJECTIONS FOR THE DELIVERY OF CHEMOTHERAPEUTIC AGENTS
摘要 Intralesional injections including poloxamer compounds and anticancer drugs are disclosed. The combination of the poloxamer-based composition with chemotherapeutic agents within the disclosed intralesional injections provides a synergistic effect, thereby allowing lower dosages of the active drugs and enhancing the treatment effectiveness. The disclosed poloxamer-based intralesional injections are employed for treating different types of cancer in humans and other animal species. The disclosed intralesional injections can be used as the sole therapy or in combination with one or more additional therapies, such as, chemotherapy, electrotherapy, immunotherapy and/or radiation therapy. The disclosed intralesional injections can be employed in virotherapy and gene therapy treatments. The disclosed intralesional injections are designed for immediate release or controlled release of the active drugs. The disclosed intralesional injections are employed for local or systemic administration of active drugs.
申请公布号 CA2936070(A1) 申请公布日期 2017.01.14
申请号 CA20162936070 申请日期 2016.07.14
申请人 PROFESSIONAL COMPOUNDING CENTERS OF AMERICA (PCCA);BEST PET RX IP, INC. 发明人 SIMMONS, CHRIS V.;CARRERO, DANNY
分类号 A61K31/77;A61K9/08;A61K45/00;A61P35/00 主分类号 A61K31/77
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