发明名称 Fizz proteins
摘要 The present invention is directed to novel polypeptides, designated FIZZ, which are secreted low molecular weight molecules showing no significant sequence homology to any known protein, and nucleic acid sequences encoding such proteins. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptide of the present invention fused to heterologous polypeptide sequences, and antibodies which bind to the polypeptides of the present invention. Methods of using FIZZ polypeptides to treat various neurotrophin-related conditions are further provided.
申请公布号 AU3654799(A) 申请公布日期 1999.11.16
申请号 AU19990036547 申请日期 1999.04.20
申请人 GENENTECH INC. 发明人 AUSTIN L. GURNEY;CAROLINE HEBERT;WILLIAM J. HENZEL;RHONA KABAKOFF;DAVID L. SHELTON;DANIEL B. TUMAS
分类号 G01N33/53;A61K38/00;A61K39/00;A61K39/395;A61K45/00;A61P43/00;C07K14/47;C12N15/09;C12N15/12 主分类号 G01N33/53
代理机构 代理人
主权项
地址