| 摘要 |
<p>A compound of the formula (I): wherein R<SUP>1</SUP>,R<SUP>2</SUP>,R<SUP>3</SUP>, R<SUP>4</SUP>,Ar, A, n and m are defined herein, is disclosed as a GlyT1 inhibitor; pharmaceutical compositions containing the compound of the formula (I) are also disclosed as are their use in medicine, for example in the treatment of schizophrenia.</p> |
| 申请人 |
MERCK SHARP & DOHME LIMITED;BLACKABY, WESLEY, PETER;HUSCROFT, IAN, THOMAS;KEOWN, LINDA, ELIZABETH;LEWIS, RICHARD, THOMAS;RAUBO, PIOTR, ANTONI;STREET, LESLIE, JOSEPH;THOMSON, CHRISTOPHER, GEORGE;THOMSON, JOANNE |
发明人 |
BLACKABY, WESLEY, PETER;HUSCROFT, IAN, THOMAS;KEOWN, LINDA, ELIZABETH;LEWIS, RICHARD, THOMAS;RAUBO, PIOTR, ANTONI;STREET, LESLIE, JOSEPH;THOMSON, CHRISTOPHER, GEORGE;THOMSON, JOANNE |
