发明名称 |
TARGET ANTIGEN DISCOVERY, PHENOTYPIC SCREENS AND USE THEREOF FOR IDENTIFICATION OF TARGET CELL SPECIFIC TARGET EPITOPES. |
摘要 |
The invention provides methods and compositions for identifying binding polypeptides (e.g., antibodies or antigen binding fragments thereof) that specifically binds to a cell-surface antigen. The methods of the invention generally comprise contacting a variegated nucleic acid-display library of binding polypeptides with a cell-surface antigen displayed on the exterior surface of a cell; and isolating from the library at least one library member that specifically binds to the cell-surface antigen on the exterior surface of the cell. |
申请公布号 |
MX2015017714(A) |
申请公布日期 |
2016.08.18 |
申请号 |
MX20150017714 |
申请日期 |
2014.06.20 |
申请人 |
X-BODY, INC. |
发明人 |
Yan CHEN;Steven SHAMAH |
分类号 |
G01N33/53;C12N15/11;G01N33/563;G01N33/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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