| 发明名称 |
DNA Antibody Constructs And Method Of Using Same |
| 摘要 |
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody. Also disclosed herein is a method of generating a synthetic antibody in a subject by administering the composition to the subject. The disclosure also provides a method of preventing and/or treating disease in a subject using said composition and method of generation. |
| 申请公布号 |
US2016311891(A1) |
申请公布日期 |
2016.10.27 |
| 申请号 |
US201415103970 |
申请日期 |
2014.12.13 |
| 申请人 |
Weiner David;Mathumani Karuppiah;Flingai Seleeke;Sardesai Niranjan |
发明人 |
Weiner David;Mathumani Karuppiah;Flingai Seleeke;Sardesai Niranjan |
| 分类号 |
C07K16/10;A61N1/32;A61M37/00;C07K16/32;C12N7/00 |
主分类号 |
C07K16/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A nucleic acid molecule encoding a synthetic antibody comprising a nucleic acid sequence having at least about 95% identity over an entire length of the nucleic acid sequence selected from the group consisting of:
(b) (c) a nucleic acid sequence as set forth in SEQ ID NO:69; (d) a nucleic acid sequence as set forth in SEQ ID NO:71; (e) a nucleic acid sequence as set forth in SEQ ID NO:73; (f) a nucleic acid sequence as set forth in SEQ ID NO:75; (g) a nucleic acid sequence as set forth in SEQ ID NO:77; (i) and (j) a nucleic acid sequence as set forth in SEQ ID NO:65. |
| 地址 |
Merion PA US |
