| 发明名称 |
METHOD OF TREATING CANCER USING SELECTIVE ESTROGEN RECEPTOR MODULATORS |
| 摘要 |
Disclosed herein are methods of treating subjects suffering from estrogen receptor positive cancer of the brain by administering a selective estrogen receptor degrader (SERM). Also disclosed are methods of treating a cancer that is resistant to an estrogen receptor modulator by administering a SERM. |
| 申请公布号 |
US2016324808(A1) |
申请公布日期 |
2016.11.10 |
| 申请号 |
US201615214187 |
申请日期 |
2016.07.19 |
| 申请人 |
Duke University |
发明人 |
Wardell Suzanne E.;Nelson Erik R.;McDonnell Donald P. |
| 分类号 |
A61K31/137;A61K9/00;A61K45/06 |
主分类号 |
A61K31/137 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a cancer in a subject, wherein the cancer is resistant to an estrogen receptor modulator, the method comprising administering a composition comprising a compound of (R)-6-{2-{ethyl[4-(2-ethylaminoethyl)benzyl]amino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol. |
| 地址 |
Durham NC US |
