| 摘要 |
<p>A controlled release capsule comprises a male plug (2) formed of a water-swellable hydrogel which is engaged within a neck portion (4) of a female body (6). The capsule is intended to deliver a pharmaceutically active material. In contact with an aqueous medium, such as in the gastro-intestinal tract, the hydrogel plug swells and becomes disengaged from the body, thereby releasing the active material. In order to facilitate insertion of the hydrogel plug, the neck portion of the body is provided with one or more vent channels (16), which extend part-way along or the entire way along the length of the neck portion. The vent channels relieve pneumatic pressure as the plug is inserted.</p> |
