METHODS AND APPARATUS FOR SPECTROSCOPIC CALIBRATION MODEL TRANSFER

摘要

A method and apparatus for measuring a biological attribute, such as the concentration of an analyte, particularly a blood analyte in tissue such as glucose. The method utilizes spectrographic techniques in conjunction with a n improved instrument-tailored calibration model. In a calibration phase, calibration model data is modified to reduce or eliminate instrument-specifi c attributes, resulting in a calibration data set modeling intra-instrument variation. In a prediction phase, the prediction process is tailored for eac h target instrument separately using a minimal number of spectral measurements from each instrument.