| 摘要 |
<p>Methods for the stabilization of microtubules involved in axonal transport are disclosed. The methods employing compounds which functionally substitute for microtubule binding protein tau are useful, inter alia, in the treatment of neurodegenerative diseases or tauopathies. Microtubule stabilizing compounds are useful for the treatment of neurodegenerative diseases, as well as schizophrenia and other mental disorders that are characterized by disruption of maintain neuronal intracellular transport, neurite architecture, or neuronal migration.</p> |
| 申请人 |
TROJANOWSKI, JOHN, Q.;SMITH, AMOS, B., III;LEE, VIRGINIA, M., Y.;THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
TROJANOWSKI, JOHN, Q.;SMITH, AMOS, B., III;LEE, VIRGINIA, M., Y. |
