| 发明名称 |
PIPERIDINYL TARGETING COMPOUNDS THAT SELECTIVELY BIND INTEGRINS. |
| 摘要 |
<p>The present invention relates to the synthesis and biological application of piperidinoyl carboxylic acid integrin antagonists affinity moiety of Formula (I) and Formula (II). These affinity moieties may be used with imaging agents or liposomes to target cells that express the alphavbeta3, alphavbeta5, or alphavbeta6 integrin receptors. Wherein W, R2, Z and q are as described in the application.</p> |
| 申请公布号 |
MXPA06009503(A) |
申请公布日期 |
2007.04.19 |
| 申请号 |
MX2006PA09503 |
申请日期 |
2004.03.29 |
| 申请人 |
JOHNSON & JOHNSON. |
发明人 |
GALEMMO, ROBERT, A., JR.;MARYANOFF, BRUCE;GHOSH, SHYAMALI;DE CORTE, BART;KINNEY, WILLIAM A.;LI, LIU;BRUNNER, LIVIA |
| 分类号 |
C07D401/12;A61K31/4523;A61K45/06;A61P13/12;A61P17/06;A61P19/02;A61P19/10;A61P35/00;C07D401/14;C07D405/14;C07D417/04;C07D471/04 |
主分类号 |
C07D401/12 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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