NON-HUMAN ANIMAL SARCOMA MODEL

摘要

The invention relates to a method of obtaining a non-human animal sarcoma model, which is characterised in that it comprises the following steps consisting in: transfecting cells derived from a pluripotent mesenchymal cell line with an expression vector containing a polynucleotide encoding a fusion protein selected from EWS-FLI1, EWS-ERG, EWS-ETV1, EWS-ETV4, EWS-FEV, EWS-ATF1, EWS-WT1, EWS-NR4A3 and EWS-DDIT3; and injecting said transfected cells into the animal that is the subject of the model. The invention also relates to the actual animal model and the applications thereof and to the transfected cell line and the applications of same.