| 摘要 |
The present invention relates to a new stereoselective process for the synthesis of 17(α)-17-acetyl-17-hydroxy-estr-4-en-3-one of formula (I), as well as to the new intermediates of the process. The 17(α)-17-acetyl-17-hy droxy-estr-4-en-3 -one (gestonorone) is an important intermediate in the synthesis of the active ingredients having progestogen activity - such as gestonorone capronate and nomegestroi acetate. Formulas (I), (II) and (III). |
