发明名称 |
Process for preparing cyclic amine substituted phenyl-alkyl-ketones |
摘要 |
<p>A process for the production of cyclic amine substituted phenyl-alkyl ketone compounds comprises aminolysis of a p-halophenylalkyl ketone with a cyclic amine in water at at least 130[deg]C. A process for the production of cyclic amine substituted phenyl-alkyl ketone compounds (I) of formula (1) comprises aminolysis of a p-halophenylalkyl ketone of formula (2) with a cyclic amine of formula (3) in water at at least 130[deg]C. [Image] [Image] R 1, R 2optionally substituted 3-20C alkylene optionally containing at least one -O-, -S- or -N(R 4); R 3optionally substituted 2-20C alkyl; R 41-3C alkyl, 3-5C alkenyl, 7-9C phenalkyl, 1-4C hydroxyalkyl or phenyl; X : halo.</p> |
申请公布号 |
EP1468994(A1) |
申请公布日期 |
2004.10.20 |
申请号 |
EP20040102145 |
申请日期 |
1997.04.24 |
申请人 |
CIBA SPECIALTY CHEMICALS HOLDING INC. |
发明人 |
HUESLER, RINALDO;SCHWABE, RUDOLF;LUISOLI, RETO |
分类号 |
C07D295/10;C07D211/14;C07D241/04;C07D265/28;C07D265/30;C07D295/112;C07D295/12;C07D295/135;C08F2/50;G03F7/028;G03F7/031;(IPC1-7):C07D295/10 |
主分类号 |
C07D295/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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