发明名称 PRODRUGS OF PYRIDONE AMIDES USEFUL AS MODULATORS OF SODIUM CHANNELS.
摘要 The invention relates to prodrug compounds of formula I: wherein R2, R3, R5, R7 and X are as defined herein. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain. The compounds of formula I possess advantageous solubility and physicochemical properties.
申请公布号 MX2016007258(A) 申请公布日期 2016.08.04
申请号 MX20160007258 申请日期 2014.12.12
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 Sara Sabina HADIDA-RUAH;Beili ZHANG;Benjamin Joseph LITTLER;Daniel T. BELMONT;Corey ANDERSON;Tim Edward ALCACIO;Julian Marian Charles GOLEC;Ali KESHAVARZ-SHOKRI
分类号 C07F9/576;A61K31/675;A61P19/02 主分类号 C07F9/576
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