发明名称 |
METHODS FOR SCREENING INHIBITORS OF TUMOUR ASSOCIATED PROTEIN AGGREGATION. |
摘要 |
The disclosure relates to the fields of protein aggregation diseases including cancer. More specifically, it concerns a screening method for identifying compounds that inhibit or disrupt co-aggregation of one or more member proteins of a disease-related protein aggregome, in particular, a tumor-associated protein aggregome. Further, disclosed are agents and compounds identified by the screening method that can be applied to prevent or to treat protein aggregation diseases, such as cancer. |
申请公布号 |
EP2689247(B1) |
申请公布日期 |
2016.10.05 |
申请号 |
EP20120710284 |
申请日期 |
2012.03.26 |
申请人 |
VIB VZW;VRIJE UNIVERSITEIT BRUSSEL;KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R&D |
发明人 |
SCHYMKOWITZ, JOOST;ROUSSEAU, FREDERIC;XU, JIE;DE SMET, FREDERIK |
分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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