发明名称 Use of PTEN-long leader sequence for transmembrane delivery of molecules
摘要 A composition for delivering cargo molecules across biological membranes is provided comprising (i) a peptide comprising consecutive amino acid residues having the sequence set forth in SEQ ID NO 1 for the transport of a cargo molecule across a biological membrane and (ii) the cargo molecule, wherein the cargo molecule is not a peptide comprising amino acid residues having the sequence set forth in SEQ ID NO 4. Methods of delivering cargo molecules across biological membranes are also provided. Methods of treating a tumor, cancer, a metabolic disorder, and a cardiovascular disorder are also provided.
申请公布号 AU2011218037(B2) 申请公布日期 2016.10.13
申请号 AU20110218037 申请日期 2011.02.17
申请人 The Trustees of Columbia University in the City of New York 发明人 Parsons, Ramon
分类号 A61K38/02 主分类号 A61K38/02
代理机构 代理人
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