| 摘要 |
An anti-diarrheic product comprises a foodstuff and an anti-rotaviral agent such as human defatted fat globule membranes, the human milk macromolecular fraction, skim milk, curd, whey, the milk mucin co mplex, the 46 Kd app.MW glycoprotein, a polypeptide having an amino acid sequence having the rotavirus binding specifi city of the 46 Kd app.MW HMFG glycoprotein or mixtures thereof. An anti-diarrheal kit comprises the anti-rotaviral agent of this invention and instructions for its use, and optionally a foodstuff. A method for inhibiting or countering rotavirus infe ction in mammalian cells comprises contacting the cells with an anti-rotaviral amount of the agent of this invention. A therap eutic method for inhibiting the onset of or countering rotavirus infection comprises administering to a subject afflicted with or at ri sk for rotavirus infections such as those occurring, for example, in infants and children (infantile gasteroenteritis) and immunodefi cient persons or those who have received a transplant, an anti-rotaviral effective amount of the agent of this invention. |
