MATERIALS AND METHODS FOR IMPROVED TISSUE ENGINEERING

摘要

The subject invention provides materials and methods for improved tissue engineering. Specifically, the current invention pertains to the identification of advantageous extracellular matrix material scaffold coatings that can be used as described herein to modulate cell seeding, attachment, culturing, proliferation, and/or differentiation to a target cell. In a further embodiment, the scaffolds of the subject invention are used to modulate stem cells. In specific embodiments, a basement membrane preparation or gelatin can be used to coat polycaprolactone (PCL) scaffolds used for seeding, attaching, culturing, proliferating, and/or differentiating cells.