Nucleophilic high molecular weight polymer functionalization through alkylation

摘要

A new and efficient method of functionalizing high molecular weight polymers through alkylation using a metal hetero alkylbase is described. This novel procedure can also be used to synthesize polymer-based macro-initiators containing radical initiating groups at the chain-ends for synthesis of block copolymers.

主权项

1. A method of functionalizing a nucleophilic high molecular weight polymer comprising the steps of:
a. dissolving the nucleophilic high molecular weight polymer in a first solvent and reacting with a metal hetero alkyl (MHTA) base, to form a first solution; b. mixing RZ with the first solution to form a second solution, wherein R is an alkyl group and Z is a leaving group; c. mixing the second solution with a second solvent to form a third solution, wherein the second solvent dissolves the MHTA, the RZ, and any reaction byproducts from steps a and b; and d. precipitating a functionalized high molecular weight polymer from the third solution.