POLYPEPTIDES, POLYNUCLEOTIDES AND COMPOSITIONS FOR USE IN THE TREATMENT OF LATENT TUBECULOSIS

摘要

The present invention is directed to a polypeptide which comprises: (i) an Rv3616c protein sequence; (ii) a variant of an Rv3616c protein sequence; or (iii) an immunogenic fragment of an Rv3616c protein sequence for use in the treatment or prevention of latent TB. In other aspects the invention is directed to associated polynucleotides, fusion proteins and methods for the treatment or prevention of latent tuberculosis.