| 发明名称 |
AFUCOSYLATED ANTI-FGFR2IIIB ANTIBODIES |
| 摘要 |
The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided. |
| 申请公布号 |
US2016339100(A1) |
申请公布日期 |
2016.11.24 |
| 申请号 |
US201615166798 |
申请日期 |
2016.05.27 |
| 申请人 |
Five Prime Therapeutics, Inc. |
发明人 |
Harding Thomas;Pierce Kristen;Patil Namrata;Brennan Thomas;Hambleton Julie |
| 分类号 |
A61K39/395;A61K31/513;A61K33/24;A61K45/06;A61K31/337 |
主分类号 |
A61K39/395 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
South San Francisco CA US |
