Blood separation and concentration system

摘要

This invention provides an apparatus and methods to consistently separate and concentrate selected blood components. The system includes, e.g., a computerized fluid handling system to transfer blood components between a centrifugal blood separation disc, containers and a concentrator.

主权项

1. An apparatus to produce concentrated blood components, which apparatus comprises:
a) a separation disc which receives blood through a first conduit, which separation disc rotates to generate centripetal force, thereby separating the blood into two or more blood components according to density; b) a control system operably connected to a first pump operably coupled to the first conduit, wherein the control system controls transfer of blood and/or blood components to the separation disc by controlling the pump; and, c) a concentrator which receives one or more of the blood components from the separation disc through a second conduit, which concentrator comprises at least one ultrafiltration membrane, which membrane comprises a retentate side and a permeate side wherein, during operation of the apparatus, the blood components being contacted to the retentate side of the membrane with a pressure gradient, thereby forcing one or more low molecular weight molecules through the membrane to a permeate side of the membrane and concentrating blood components.