| 发明名称 |
Thioketals and thioethers for inhibiting the expression of VCAM-1 |
| 摘要 |
Thioketals and thioethers are provided that inhibit the expression of VCAM-1, and which can be used in the treatment of VCAM-1 mediated diseases including inflammatory disorders, cardiovascular diseases, occular diseases, autoimmune diseases, neurological disorders, and cancer. The compounds also can be used to treat hyperlipidemia and/or hypercholesterolemia.
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| 申请公布号 |
US2005171028(A1) |
申请公布日期 |
2005.08.04 |
| 申请号 |
US20050054644 |
申请日期 |
2005.02.08 |
| 申请人 |
ATHEROGENICS PHARMACEUTICALS, INC. |
发明人 |
MENG CHARLES Q.;HOONG LEE K.;SOMERS PATRICIA K.;SIKORSKI JAMES A. |
| 分类号 |
C07C323/20;C07C323/60;C07H15/203;(IPC1-7):A61K31/704;C07H17/02;C07H5/04 |
主分类号 |
C07C323/20 |
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