METHOD OF CONSERVING AND PREPARING TISSUE OR CELLS FOR TRANSFER, TRANSPLANT, RE-IMPLANTATION, FURTHER STUDY OR THE LIKE

摘要

A method of conserving and preparing tissue or cells, other than cardiac tissue or cardiac cells, for transfer, transplant, re-implantation, further study or the like, includes administering to tissue or cells an effective amount of a composition including a polypeptide agent including thymosin beta 4 (TB4), an isoform, analogue or derivative of TB4 having biological activity of TB4, an N-terminal variant of TB4 having biological activity of TB4, a C-terminal variant of TB4 having biological activity of TB4, LKKTET or a conservative variant thereof, LKKTNT or a conservative variant thereof, KLKKTET or a conservative variant thereof, LKKTETQ or a conservative variant thereof, TB4 sulfoxide, TB4¿ala?, TB9, TBIO, TB11, TB12, TB13, TB14, TB15, gelsolin, vitamin D binding protein (DBP), profilin, cofilin, adsevertin, propomyosin, fincilin, depactin, Dnasel, vilin, fragmin, severin, capping protein, ß-actinin or acumentin, or a stimulating agent that stimulates production of the polypeptide agent, or a conservative variant thereof, in the tissue or cells.