发明名称 |
CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS |
摘要 |
<p>The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity.
The carboxamide compounds are compounds of the general formula I
in which R 1 , R 2 , R 3a , R 3b , W, V and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof.</p> |
申请公布号 |
EP2121653(A1) |
申请公布日期 |
2009.11.25 |
申请号 |
EP20070866322 |
申请日期 |
2007.12.28 |
申请人 |
ABBOTT GMBH & CO. KG |
发明人 |
KLING, ANDREAS;HORNBERGER, WILFRIED;MACK, HELMUT;MOELLER, ACHIM;NIMMRICH, VOLKER;SEEMANN, DIETMAR;LUBISCH, WILFRIED |
分类号 |
C07D401/04;A61K31/4439;A61P25/00;C07D401/14;C07D405/14;C07D409/14;C07D493/04 |
主分类号 |
C07D401/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|