APPARATUS AND METHOD FOR EXTRACTING BIOLOGICALLY ACTIVE SUBSTANCES THROUGH MAGNETIC BEADS METHOD

摘要

The present invention provides an efficient apparatus for extracting biologically active substances through a magnetic particle method, comprising a magnetic needle, a magnetic needle moving mechanism, a sleeve and a sleeve moving mechanism and a vibration mechanism, a bracket, a positioning mechanism; the vibration mechanism is capable of generating vibrations to enable the sleeve moving mechanism to make upward and downward vibrations; wherein the magnetic needle can vertically insert into and move out of the sleeve; the sleeve can vertically insert into and move out of a sample treatment area; and the vibration mechanism comprises a lever bar, a movable fulcrum and a rotary mechanism. The present invention further provides an instrument comprising the apparatus for extracting biologically active substances. The present invention further provides a method for extracting and purifying biologically active substances using the apparatus or the instrument for extracting biologically active substances. The vibration frequency and amplitude of the apparatus and the instrument can be optionally adjusted, and the range of adjustments for the amplitude is greatly extended, so the apparatus and the instrument exhibit such advantages as making only small noise and have a long service life.

主权项

1. An apparatus for extracting biologically active substances comprising:
A magnetic needle (7) and a magnetic needle moving mechanism (6); the magnetic needle moving mechanism comprises a magnetic needle bracket and a magnetic needle lifting mechanism, and the magnetic needle is detachably secured onto the magnetic needle bracket; wherein, upward and downward movements of the magnetic needle lifting mechanism enable the magnetic needle to vertically insert into and move out of a sleeve; A sleeve (4) and a sleeve moving mechanism (3); the sleeve moving mechanism comprises a sleeve bracket and a sleeve lifting mechanism, and the sleeve is detachably secured on the sleeve bracket; wherein, upward and downward movements of the sleeve lifting mechanism enable the sleeve to vertically insert into and move out of a sample treatment area; additionally, the sleeve moving mechanism is capable of making upward and downward vibrations; A bracket (13) for holding the magnetic needle moving mechanism (6) and the sleeve moving mechanism (3); and a vibration mechanism (19) capable of generating and outputting vibrations so as to enable the sleeve moving mechanism (16) to make upward and downward vibrations; wherein the vibration mechanism comprises a lever bar, a movable fulcrum and a rotary mechanism; wherein the rotary mechanism has a wheel and an axis; when the rotary mechanism turns around the axis, the outer rim of its wheel can push the lever bar to turn around the movable fulcrum, thereby generating vibrations; wherein the vibration mechanism is disposed above the bracket (13).