The present invention relates to the field of microfluidics and in particular to methods for co-localizing a particle comprising DNA and/or RNA with a known barcode oligonucleotide. Thereby, the transcriptome or DNA of a cell can be barcoded and correlated to a cell phenotype or examined for the effect of a drug on the cell. The invention also provides microfluidic devices and systems having properties which make them particularly suitable for use in the methods of the invention.
申请公布号
WO2016207441(A1)
申请公布日期
2016.12.29
申请号
WO2016EP64877
申请日期
2016.06.27
申请人
EUROPEAN MOLECULAR BIOLOGY LABORATORY
发明人
UTHARALA, Ramesh;CHAIPAN, Chawaree;NÖGEL, Lukas;MERTEN, Christoph A.