COMPOSITIONS AND METHODS FOR INJECTABLE COMPOSITION FOR AN ACCOMMODATING INTRAOCULAR LENS

摘要

The present disclosure relates to injectable compositions and methods of making injectable compositions of moisture curing siloxane polymers for forming accommodating intraocular lenses. In certain embodiments, the moisture curing siloxane polymers are comprised of an organosilicon compound and a hydrolytically sensitive siloxane moiety and have a specific gravity of greater than about 0.95, a number average molecular weight (Mn) greater than about 5,000 or about 20,000 and a weight average molecular weight (Mw) greater than about 20,000 or about 40,000. The disclosure includes accommodating intraocular lenses formed from moisture curing siloxane polymers and having a modulus of elasticity of less than about 6kPa, less than 20% post-cure extractables, refractive index ranging from 1.4 to 1.5 and dioptric range of accommodation of 0D to 10D.