发明名称 Enhanced circulation effector composition and method
摘要 A liposome composition comprising small, surface-bound effector molecules is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal ends of the polymer chains. In one embodiment, the effector is polymyxin B, for treatment of septic shock.
申请公布号 US2001043929(A1) 申请公布日期 2001.11.22
申请号 US20010877978 申请日期 2001.06.08
申请人 ALZA CORPORATION 发明人 ZALIPSKY SAMUEL;WOODLE MARTIN C.;MARTIN FRANCIS J.;BARENHOLZ YECHEZKEL;BERCOVIER HERVE
分类号 A61K9/127;A61K47/48;(IPC1-7):A61K39/395;A61K31/715 主分类号 A61K9/127
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