| 发明名称 |
IMIDAZOLE DERIVATIVES AS MGLUR5 ANTAGONISTS |
| 摘要 |
The present invention relates to imidazole derivatives of the general formula wherein R1, R2, R3, and R4 are as defined in the specification and to pharmaceutically acceptable salts thereof. Compounds of formula I are metabotropic glutamate receptor antagonists. They can be used in the treatment or prevention of mGluR5 receptor mediated disorders. |
| 申请公布号 |
HRP20130657(T1) |
申请公布日期 |
2013.08.31 |
| 申请号 |
HR2013P000657T |
申请日期 |
2013.07.10 |
| 申请人 |
F. HOFFMANN - LA ROCHE AG |
发明人 |
JAESCHKE, GEORG;LINDEMANN, LOTHAR;VIEIRA, ERIC;WICHMANN, JUERGEN |
| 分类号 |
C07D401/04;A61K31/4439;A61P25/00;C07D401/14;C07D403/04 |
主分类号 |
C07D401/04 |
| 代理机构 |
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