发明名称 |
EXPANSION OF ALLOANTIGEN-REACTIVE REGULATORY T CELLS |
摘要 |
The present disclosure relates generally to the manufacture of regulatory T cells (Tregs) for use in immunotherapy. In particular, the present disclosure relates to robust approaches for the expansion of alloantigen-reactive Tregs ex vivo. Alloantigen-reactive Tregs produced in this way are suitable for the induction and/or maintenance of immunologic tolerance in recipients of allogeneic transplants. |
申请公布号 |
WO2013131045(A1) |
申请公布日期 |
2013.09.06 |
申请号 |
WO2013US28734 |
申请日期 |
2013.03.01 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
TANG, QIZHI;BLUESTONE, JEFFREY, A. |
分类号 |
C12N5/0783;A61K35/14;A61P37/00;C12N5/0781 |
主分类号 |
C12N5/0783 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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