发明名称 |
ENHANCED PROTEIN EXPRESSION |
摘要 |
The present invention relates in general to bacterial cells having genetic alterations that result in increased expression of a protein of interest and methods of making and using such cells. Aspects of the present invention include altered Gram positive microorganismshaving one or more a genetic alterations that reduce the expression of a gene in the sin operon, thereby resulting in the enhanced expression of one or more proteins of interest. |
申请公布号 |
WO2016099917(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
WO2015US63636 |
申请日期 |
2015.12.03 |
申请人 |
DANISCO US INC |
发明人 |
BONGIORNI, CRISTINA;GONZALES CAGUIAT, RODANTE;NMI FIORESI, CAROL;SCHMIDT, BRIAN F.;VAN KIMMENADE, ANITA;ZHU, CHAO |
分类号 |
C07K14/32;C12N1/21;C12P21/02;C12R1/125 |
主分类号 |
C07K14/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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