| 发明名称 |
Combination Immunotherapy for the Treatment of Cancer |
| 摘要 |
Agonists to ICOS in combination with a blocking agent to a T cell inhibitory receptor (e.g., CTLA-4, PD-1, etc.) are demonstrated herein to be useful for the treatment of tumors. |
| 申请公布号 |
US2016244524(A1) |
申请公布日期 |
2016.08.25 |
| 申请号 |
US201615145780 |
申请日期 |
2016.05.03 |
| 申请人 |
Board of Regents, The University of Texas System ;Memorial Sloan-Kettering Cancer Center |
发明人 |
Allison James;Sharma Padmanee;Quezada Sergio A.;Fu Tihui |
| 分类号 |
C07K16/28;A61K38/17;A61K39/395 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating cancer in a patient comprising administering to the patient simultaneously or sequentially a composition comprising a blocking agent to a T cell inhibitory receptor and an agonist to ICOS. |
| 地址 |
Austin TX US |
